Hormonal regulation of regucalcin gene expression: involvement in cell metabolism

نویسندگان

چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Hormonal regulation of regucalcin gene expression: involvement in cell metabolism

Regucalcin (RGN/SMP30) and its gene (rgn)are identified in over 15 species consisting of regucalcin family, and its gene is localized on X chromosome. Regucalcin has been shown to play a multifunctional role in many tissues and cell types. Hormonal regulations of regucalcin gene expression are mediated through various transcription factors (including AP-1, NF1-A1, RGPR-p117 and other), which ar...

متن کامل

Hormonal regulation of regucalcin mRNA expression in osteoblastic MC3T3-E1 cells.

The effect of various hormones on regucalcin mRNA expression in osteoblastic MC3T3-E1 cells in vitro was investigated. Cells with subconfluency were cultured for 24 or 48 h in a medium containing either vehicle or various hormones without fetal bovine serum. Regucalcin mRNA expression was significantly increased after culture with parathyroid hormone (synthetic human PTH; 10(-7) M), insulin-lik...

متن کامل

The potential role of regucalcin in kidney cell regulation: Involvement in renal failure (Review).

The kidneys play a physiologic role in the regulation of urine formation and nutrient reabsorption in the proximal tubule epithelial cells. Kidney development has been shown to be regulated through calcium (Ca2+) signaling processes that are present through numerous steps of tubulogenesis and nephron induction during embryonic development of the kidneys. Ca2+-binding proteins, such as calbindin...

متن کامل

Hormonal regulation of steroidogenic enzyme gene expression in Leydig cells.

In normal mouse Leydig cells, steady state levels of mRNA of CYP11A, 3β-hydroxysteroid dehydrogenase Δ⁵- >Δ⁴-isomerase (3βHSD), and CYP17 are differentially regulated. There is high basal expression of 3βHSD and CYP11A mRNA, while expression of CYP17 mRNA is absolutely dependent on cAMP stimulation. cAMP is required for maximal expression of all three enzymes. The expression of CYP11A in normal...

متن کامل

Regulation of Bone Metabolism

Bone is formed through the processes of endochondral and intramembranous ossification. In endochondral ossification primary mesenchymal cells differentiate to chondrocytes and then are progressively substituted by bone, while in intramembranous ossification mesenchymal stem cells (MSCs) differentiate directly into osteoblasts to form bone. The steps of osteogenic proliferation, differentiation,...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Hormonal Studies

سال: 2013

ISSN: 2052-8000

DOI: 10.7243/2052-8000-1-1